DETERMINATION OF BIOLOGICAL ACTIVITIES OF 2(3-OXO-2H-BENZO (1,4) THIAZINE 2 IL)ACETIC ACID USING PASS ONLINE AND MOLECULAR DOCKING
In this article, the potential biological activity of 2(3-oxo-2H-benzo[1,4]thiazin-2-yl)acetic acid was studied using in silico methods.
PASS Online and its integrated predictive models were used to evaluate the pharmacological properties, toxicity level, and ADMET
parameters of the molecule. Molecular docking calculations were performed with a number of target enzymes and proteins to
determine the proximity to active sites, ligand–receptor interactions, and binding energies. The results showed that this compound
has a high probability of possessing antibacterial, antioxidant, and potential antitumor activity. The docking results also confirmed
that it forms stable hydrogen bonds and hydrophobic interactions through active pharmacophore groups. The results of the study
indicate that this compound can be considered as a promising ligand in future pharmaceutical research.
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