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USE OF ELISA IMMUNO ASSAY FOR EARLY DETECTION OF ANTIBODIES TO TREPONEMA PALLIDUM

enzyme-linked immunosorbent assay (ELISA), antibodies, virus, syphilis, WHO.

Authors

Syphilis, which is a type of infection caused by the bacterium Treponema pallidum, is mainly transmitted through sexual activity, but vertical transmission from the mother to the fetus and through blood transfusions are also possible ways of infection. This disease is described by its chronic character, which causes a gradual damage to different organs and the development of severe complications. The worldwide incidence is still very high, with approximately 7. 1 million adults aged 15 to 49 who were diagnosed with syphilis in 2020, as reported by the World Health Organization. Effective diagnosis of syphilis is based on laboratory tests, especially immunochemical methods, which detect the specific antibodies in the blood that are evidence of the infection. This article is about the new ways in which the enzyme immunoassay techniques have been improved to make the early detection of the antibodies to Treponema pallidum possible, thus helping in the prevention and control of its spread.