PHYSICOCHEMICAL CHARACTERIZATION OF THE COORDINATION BEHAVIOR OF GLUTARIC AND 4- PYRIDINE MONOCARBOXYLIC ACIDS IN Co(II) AND VO(II) COMPLEXES
In this article, the physicochemical properties and structure of mixed-ligand coordination compounds formed by Co(II) and VO(II)
ions with bioligands, glutaric and 4-pyridinemonocarboxylic acids, were analyzed using elemental analysis, powder X-ray
diffraction, IR spectroscopy, and thermal analysis.
1. Frei A. Metal complexes as a promising source for new antibiotics // Chem. Sci. 2020. Т. 11, № 10. С. 2627–2639. DOI:
10.1039/C9SC06460E.
2. Yadav A., Yadav S., Kamboj A., Phogat B., Poonia K. Bioactivity profile of Schiff Base complexes of copper, cobalt, zinc,
and nickel: A five-year review // Inorg. Chem. Commun. 2025. Т. 181. С. 115151. DOI: 10.1016/j.inoche.2025.115151.
3. Parveen S. Biophysical and theoretical investigation of benzo[c]coumarin functionalized Schiff base with human serum
albumin // Chem. Pap. 2021. Т. 75, № 6. С. 2339–2351. DOI: 10.1007/s11696-020-01496-5.
4. Deswal Y. Cobalt(II), nickel(II), copper(II) and zinc(II) complexes of thiadiazole based Schiff base ligands: Synthesis,
structural characterization, DFT, antidiabetic and molecular docking studies // J. Mol. Struct. 2022. Т. 1253. С. 132266. DOI:
10.1016/j.molstruc.2021.132266.
5. Chaudhary A. Explorative study of a new Schiff base and its Co2+, Mn2+ and Fe3+ complexes: synthesis, characterization,
antimicrobial, anticancer, DNA cleavage activities and DFT calculations // Inorg. Chem. Commun. 2026. Т. 186. С. 116179.
DOI: 10.1016/j.inoche.2026.116179.
6. Begum A. A comprehensive review of anti-diabetic activity of vanadium-based complexes via PTP-1B inhibition mechanism
// Results Chem. 2023. Т. 6. С. 101154. DOI: 10.1016/j.rechem.2023.101154.
7. Alsuhaibani A. M., AlShawi A. H., Gaber A., Shakya S., Refat M. A theoretical study on a new drug combines between
vanadyl sulfate and vitamin E in a single component: A novel antioxidant medication in female reproductive health // Bull.
Chem. Soc. Ethiop. 2024. DOI: 10.4314/bcse.v38i4.14.
8. Deswal Y. Cobalt(II), nickel(II), copper(II) and zinc(II) complexes of thiadiazole based Schiff base ligands: Synthesis,
structural characterization, DFT, antidiabetic and molecular docking studies // J. Mol. Struct. 2022. Т. 1253. С. 132266. DOI:
10.1016/j.molstruc.2021.132266.
9. Ismail K., Behzad M., Ghasemi L., Hassan S. Design, synthesis, and molecular docking of VO(II)-chitosan Schiff base
nanoparticles for targeted colon cancer, antidiabetic, and antimicrobial applications // Int. J. Biol. Macromol. 2025. С.
147138. DOI: 10.1016/j.ijbiomac.2025.147138.
10. Lopes J. и др. Novel 8-Hydroxyquinoline-Derived V(IV)O, Ni(II), and Fe(III) Complexes: Synthesis, Characterization, and
In Vitro Cytotoxicity Against Tumor Cells // Inorganics. 2025. DOI: 10.3390/inorganics13050150.
11. El‐Gammal O., El-Nawawy M., Gomaa H., Ismael B. Synthesis, spectral, DFT, intrinsic constant of DNA binding and
antioxidant activity of vanadyl (IV)2+ complexes of a symmetrical bis thiosemicarbazides // J. Mol. Struct. 2023. DOI:
10.1016/j.molstruc.2023.135335.
12. Ashraf T., Ali B., Qayyum H., Haroone M. S., Shabbir G. Pharmacological aspects of schiff base metal complexes: A critical
review // Inorg. Chem. Commun. 2023. Т. 150. С. 110449. DOI: 10.1016/j.inoche.2023.110449.
13. Fabbrizzi L. Beauty in Chemistry: Making Artistic Molecules with Schiff Bases // J. Org. Chem. 2020. Т. 85, № 19. С.
12212–12226. DOI: 10.1021/acs.joc.0c01420.
14. Gazieva A., Shabilalov A., Fatkhullaeva M. Synthesis, study of the structure and acute toxicity of the coordinating
compounds of Co(II) with succinic and pantotenic acids. // Pharmacology OnLine. 2021. T.2. C. 1346-1355.
15. Gazieva A., Shabilalov A., Fatkhullaeva M., Pulatova G. Synthesis and study of coordinating compounds of VO(II), Ni(II)
and Co(II) with glutaric and 3-pyridinemonocarboxylic acids // UniChem. 2022. Т. 98, № 8–2. DOI:
10.32743/UniChem.2022.98.8.14114.
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