REDUCING OBSTETRIC AND PERINATAL RISK DURING IVF: STRATEGY FOR TRANSFERING A SINGLE EMBRYO AT THE BLASTOCYST STAGE TO AVOID MULTIPLE PREGNANCY

IVF was officially approved in Uzbekistan in 2019. All over the world, including here, at the initial stage of IVF implementation, preference was given to the transfer of two or more embryos at the cleavage stage. Low implantation rates of cleavage stage transfers have led to the transfer of multiple embryos to achieve an acceptable clinical pregnancy rate, leading to an increase in the number of multiple pregnancies. Multiple pregnancies entail preterm birth, which leads to the birth of premature babies with low body weight and a high likelihood of illness, disability, and mortality. Embryo transfer at the blastocyst stage allows selective transfer of a single embryo, which increases the implantation potential, increases clinical pregnancy rates, simultaneously increases the number of singleton pregnancies. The frequency of multiple pregnancies with IVF decreases.