TERPENOIDS, CHEMICAL COMPOSITION OF ESSENTIAL OIL AND ANTIMICROBIAL ACTIVITY OF FERULA FERGANENSIS ROOT

Ferula ferganensis; Essential oil; Antibacterial activity; Antifungal activity; KSC, GC-MS.

Authors

  • Nargiza YULDASHEVA Bakhrom KOMILOV Acad. S.Yu.Yunusov Institute of Chemistry of Plant Substances. Academy of Sciences of the Republic of Uzbekistan,. Junior Researcher, Acad. S.Yu. Yunusov Institute of Chemistry of Plant Substances. Academy of Sciences of the Republic of Uzbekistan, Senior Research Fellow (PhD), Associate Professor, Uzbekistan
  • Komila ESHBAKOVA Sherali SULAYMONOV Acad. S.Yu. Yunusov Institute of Chemistry of Plant Substances. Academy of Sciences of the Republic of Uzbekistan, Senior Research Fellow (PhD), Associate Professor,Senior Lecturer, Namangan State University , Uzbekistan
  • Bohodir MAMARASULOV Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan, Senior Research Fellow PhD , Uzbekistan

Continuing the study of the chemical composition of the Ferula ferganensis plant, terpenoids were isolated from the root using silica gel KSC and column chromatography from the chloroform fraction. The sesquiterene esters of three carotenoids were isolated from the chloroform fraction with a mixture of benzene and ethyl acetate (25:1-6:1) and analyzed hexane fraction by GC and GC/MS to determine the composition of the volatile ester, and 63 components were identified. This study revealed that the ether oil of F. ferganensis contains biologically active substances, especially antimicrobial agents.