CLINICAL CHARACTERISTICS OF PATIENTS WITH OSTEOARTHRITIS
This article presents the clinical characteristics of patients with osteoarthritis. The study analyzes the factors contributing to disease development, clinical manifestations, radiological and laboratory findings. Differences related to age, gender, and comorbidities are also examined. The results are important for the early diagnosis of osteoarthritis and the development of individualized treatment strategies.This article presents a clinical analysis of patients diagnosed with osteoarthritis (OA). The study involved 81 women aged between 47 and 75 years, with a mean age of 57.7±7.55 years. All participants were in the postmenopausal period. The research examines the clinical and radiological features of OA, disease duration, the number and type of affected joints, as well as comorbid conditions. Most patients showed combined involvement of the knee and hip joints, with polyosteoarthritis being prevalent. Key clinical symptoms included joint pain, restricted mobility, and deformity. The article outlines diagnostic criteria and treatment approaches, including NSAIDs, physiotherapy, and chondroprotective therapy. The importance of a phenotype-based approach is highlighted for optimizing individualized diagnosis and management. In conclusion, osteoarthritis is a multifactorial condition, and thorough clinical characterization is crucial for effective treatment planning
1. Allen K.D., Golightly Y.M. Epidemiology of osteoarthritis: state of the evidence. Curr Opin Rheumatol. 2015; 27(3):276– 283. doi:10.1097/BOR.0000000000000161.
2. Bijlsma J.W.J., Berenbaum F., Lafeber F.P.J.G. Osteoarthritis: an update with relevance for clinical practice. The Lancet. 2011; 377(9783):2115–2126. doi:10.1016/S0140-6736(11)60243-2.
3. Dell’Isola A., Allan R., Smith S.L., Marreiros S.S., Steultjens M. Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature. BMC Musculoskelet Disord. 2016;17:425. doi:10.1186/s12891-016-1286.
4. Deveza L.A., Melo L., Yamato T.P., Mills K., Hunter D.J. Knee osteoarthritis phenotypes and their relevance for outcomes: a systematic review. Osteoarthritis Cartilage. 2017;25(12):1926–1941. doi:10.1016/j.joca.2017.08.009.
5. Hame S.L., Alexander R.A. Knee osteoarthritis in women. Curr Rev Musculoskelet Med. 2013;6(2):182–187. doi:10.1007/s12178-013-9164-0.
6. 9. Kluzek S., Sanchez-Santos M.T., Leyland K.M., Judge A., Spector T.D., Hart D.J., Cooper C., Newton J.L., Arden N.K. Painful knee but not hand osteoarthritis is associated with higher all-cause mortality: a UK population-based cohort study. Ann Rheum Dis. 2016;75(11):1793–1799. doi:10.1136/annrheumdis-2015-207305.
7. 10. Murphy L., Helmick C.G. The impact of osteoarthritis in the United States: a population-health perspective. Am J Nurs. 2012;112(3 Suppl 1): S13–S19. doi:10.1097/01.NAJ.0000412646.80054.21.
8. Palazzo C., Nguyen C., Lefevre-Colau M.M., Rannou F., Poiraudeau S. Risk factors and burden of osteoarthritis. Ann Phys Rehabil Med. 2016;59(3):134–138. doi:10.1016/j.rehab.2016.01.006.
9. Puenpatom R.A., Victor T.W. Increased prevalence of metabolic syndrome in individuals with osteoarthritis: an analysis of NHANES III data. Postgrad Med. 2009; 121(6):9–20. doi:10.3810/pgm.2009.11.2073.
10. Silverwood V., Blagojevic-Bucknall M., Jinks C., Jordan J., Protheroe J., Jordan K. Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage. 2015;23(4):507–515. doi:10.1016/j.joca.2014.11.019.
11. Turkiewicz A., Petersson I.F., Björk J., Hawker G., Dahlberg L.E., Lohmander L.S., Englund M. Current and future impact of osteoarthritis on health care: a population-based study with projections to year 2032. Osteoarthritis Cartilage. 2014;22(11):1826–1832. doi:10.1016/j.joca.2014.07.015.
12. Болезни костно-мышечной системы и соединительной ткани (М00-М99) / Международная статистическая классификация болезней и проблем, связанных со здоровьем; 10-е издание, т. 1 // М.: Медицина, 1995. – С.643-698
13. Гайдаш И.С., Зайцев В.В., Шубина О.С. и др. Рентгенологическая характеристика остеоартроза. Гений ортопедии. 2022;28(3):307–313. doi:10.18019/1028-4427-2022-28-3-307-313.
14. Internet manbalari: a. https://www.ncbi.nlm.nih.gov/books/NBK482326/ b. https://diseases.medelement.com/disease/остеоартроз-рекомендации-рф/15094. c. Wikipedia. Available from: https://en.wikipedia.org/wiki/Osteoarthritis
Copyright (c) 2025 «ACTA NUUz»
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
.jpg)
1.png)
