REACTIONS OF PYRIDINE-BASED QUATERNARY AMMONIUM SALTS WITH CHITOSAN AND THEIR BIOLOGICAL ACTIVITY
Reactions of some esters of pyridine with monochloroacetic acid were carried out. As a result of the reactions, the quaternary ammonium salt of pyridine was obtained. Alternative reaction conditions were studied, and the efficiency of the obtained salts was calculated. It is known that chitosan has high biological activity, but its insolubility in water limits its application areas. Therefore, the synthesis of a quaternary ammonium salt based on chitosan is considered an important reaction. The quaternary ammonium salt of chitosan was synthesized based on pyridine's quaternary ammonium salt. It was found that the positively charged compound of chitosan has antibacterial properties. The synthesized compounds were analyzed using physicochemical methods, including IR and NMR spectroscopy. The results indicated that the quaternary ammonium salt of chitosan was successfully formed.
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