Tabiiy fanlar

ХИМИЧЕСКИЙ СОСТАВ И БИОЛОГИЧЕСКАЯ АКТИВНОСТЬ ЛИСТЬЕВ RHUS GLABRA

Anacardiaceae, Rhus glabra, extraction, flavonoids, hydrolyzable tannins, high-performance liquid chromatography (HPLC), mass spectrometry, hepatoprotective activity.

Authors

For the first time, a polyphenol complex-provisionally named Glabtan-was isolated from the leaves of the local plant Rhus glabra (family Anacardiaceae), and its polyphenolic composition was determined. To study the chemical composition of the obtained polyphenol complex, high-performance liquid chromatography (HPLC) was used. As a result of the HPLC analysis, 24 fractions were obtained, among which 7 types of hydrolyzable tannins were identified in high yield. The hepatoprotective activity of Glabtan was studied using a model of acute toxic hepatitis. The experimental results confirmed the potential of Glabtan as an effective agent for the treatment of toxic liver damage