СИНТЕЗ ОСНОВАНИЙ ШИФФА НА ОСНОВЕ ЭФИРОВ П-АМИНОБЕНЗОЙНОЙ КИСЛОТЫ
В данной работе впервые проведена конденсация эфиров п-аминобензойной кислоты с ароматическими альдегидами,
содержащими различные функциональные группы. Изучены условия синтеза оснований Шиффа и найдены
оптимальные условия. Продукты синтеза были выделены и изучена их структура с использованием современных
физических методов исследования ИК- и 1 H ЯМР-спектроскопии.
1. Yadav L. D. S., Yadav B. S., Rai V. K. A novel salicylaldehyde based mineral supported expedient synthesis of
benzoxazinone nucleosides //Tetrahedron letters. – 2004. – Т. 45. – №. 28. – P. 4251-4258.
2. Rezvani Z. et al. Liquid crystalline properties of copper (II) complexes derived from azo-containing salicylaldimine ligands
//Polyhedron. – 2006. – Т. 25. – №. 9. – P. 1915-1920.
3. Przybylski P. et al. Biological properties of Schiff bases and azo derivatives of phenols //Current Organic Chemistry. –
2009. – Т. 13. – №. 1. – P. 668-680.
4. Abd El-Halim H. F. et al. Spectroscopic and biological activity studies on tridentate Schiff base ligands and their transition
metal complexes //European Journal of Chemistry. – 2011. – Т. 2. – №. 2. – P. 178-188.
5. Choudhary M., Patel R. N., Rawat S. P. Synthesis, electrochemical, structural, spectroscopic and biological activities of
mixed ligand copper (II) complexes with 2-{[(Z)-(5-bromo-2-hydroxyphenyl) methylidene] amino} benzoic acid and
nitrogenous bases //Journal of Molecular Structure. – 2014. – Т. 1060. – P. 197-207.
6. Bases S. A Short Survey on an Evergreen Chemistry Tool/Wenling Qin, Sha Long, Mauro Panunzio, Stefano Biondi
//Molecules. – 2013. – Т. 18. – P. 12264-12289.
7. Trujillo-Ferrara J., Cano L. M., Espinoza-Fonseca M. Synthesis, anticholinesterase activity and structure–activity
relationships of m-aminobenzoic acid derivatives //Bioorganic & medicinal chemistry letters. – 2003. – Т. 13. – №. 10. – P.
1825-1827.
8. Panneerselvam P. et al. Synthesis of Schiff bases of 4-(4-aminophenyl)-morpholine as potential antimicrobial agents
//European journal of medicinal chemistry. – 2005. – Т. 40. – №. 2. – P. 225-229.
9. Correa-Basurto J. et al. p–Aminobenzoic acid derivatives as acetylcholinesterase inhibitors //European journal of medicinal
chemistry. – 2005. – Т. 40. – №. 7. – P. 732-735.
10. Shi L. et al. Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde //European journal
of medicinal chemistry. – 2007. – Т. 42. – №. 4. – P. 558-564.
11. Yang H. J. et al. The rapid synthesis of Schiff-base without solvent under microwave irradiation //Chinese chemical letters.
– 2002. – Т. 13. – №. 1. – С. 3-6.
12. Negm N. A., Zaki M. F. Structural and biological behaviors of some nonionic Schiff-base amphiphiles and their Cu (II) and
Fe (III) metal complexes //Colloids and Surfaces B: Biointerfaces. – 2008. – Т. 64. – №. 2. – P. 179-183.
13. Naeimi H., Salimi F., Rabiei K. Mild and convenient one pot synthesis of Schiff bases in the presence of P2O5/Al2O3 as
new catalyst under solvent-free conditions //Journal of Molecular Catalysis A: Chemical. – 2006. – Т. 260. – №. 1-2.–
P.100-104.
14. Muhamedjonova F.Z., P-aminobenzoy kislotasi va butil efirining 5-bromo-salitsilaldegid bilan reaksiyasi. Kimyoning
dolzarb muammolari mavzusidagi respublika ilmiy-amaliy anjumani. Toshkent 2021 yil.
15. F.Z. Muhamedjanova, F.A. Sapaev, T.S. Xoliqov. 2-amino-2-oksoetil-4-aminobenzoatning 4-gidroksobenzaldegid bilan
reaksiyasi. Zamonaviy kimyoning dolzarb muammolari mavzusidagi ilmiy-amaliy anjumani. Buxoro 2020 yil.
16. Muhamedjonova F.Z., Bobonazarova S.X., Sapaev F.A., Xoliqov T.S. p–Aminobenzoy kislotaning gidroksibenzaldegid
bilan reaksiyasi. Funksional polimerlar fanining zamonaviy holati va istiqbollari mavzusidagi ilmiy-amaliy anjumani.
Toshkent 2020 yil.
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