OG‘IR IONLAR TERAPIYASIDA QOLDIQ RADIOAKTIVLIK VA XODIMLARNING NURLANISHI: MODELLASHTIRISH USULI YORDAMIDA TADQIQOT
##submission.downloads##
Ogʻir ionlardan foydalanilgan ionli radioterapiya yuqori aniqlikdagi davolashni taʼminlaydi, biroq u tibbiyot xodimlari uchun nurlanish manbayi boʻlishi mumkin boʻlgan qoldiq radioaktivlik bilan kechadi. Ushbu ishda FLUKA kodidan foydalangan holda Monte-Karlo modellashtirish yordamida ionli davolash xonasida qoldiq radioaktivlikning tahlili oʻtkazildi. Tadqiqot qisqa muddatli va uzoq muddatli nurlanish stsenariylarini oʻz ichiga olib, xodimlarga boʻlgan radiatsion taʼsirni baholashga qaratilgan. Natijalar koʻplab radionuklidlarning hosil boʻlishini koʻrsatdi, bu esa ion terapiyasi markazlarida kasbiy nurlanishni kamaytirish va xavfsizlikni oshirish boʻyicha chora-tadbirlarni taklif qilishga imkon berdi.
1. Battistoni G, Bauer J, Boehlen TT, et al (2016) The FLUKA Code: An Accurate Simulation Tool for Particle Therapy. Frontiers in Oncology 6:
2. Ando K, Kase Y (2009) Biological characteristics of carbon-ion therapy. International journal of radiation biology 85:715– 728
3. Schardt D, Elsässer T, Schulz-Ertner D (2010) Heavy-ion tumor therapy: Physical and radiobiological benefits. Reviews of modern physics 82:383–425 4. Durante M, Debus J, Loeffler JS (2021) Physics and biomedical challenges of cancer therapy with accelerated heavy ions. Nature Reviews Physics 3:777–790
5. Thomadsen B, Nath R, Bateman FB, et al (2014) Potential hazard due to induced radioactivity secondary to radiotherapy: The report of task group 136 of the American Association of Physicists in Medicine. Health physics 107:442–460
6. Suzuki M, Kase Y, Yamaguchi H, et al (2000) Relative biological effectiveness for cell-killing effect on various human cell lines irradiated with heavy-ion medical accelerator in Chiba (HIMAC) carbon-ion beams. International Journal of Radiation Oncology* Biology* Physics 48:241–250
7. Yonekura Y, Tsujii H, Hopewell JW, et al (2016) Radiological protection in ion beam radiotherapy: practical guidance for clinical use of new technology. Annals of the ICRP 45:138–147
8. Schulz-Ertner D, Tsujii H (2007) Particle radiation therapy using proton and heavier ion beams. Journal of clinical oncology 25:953–964 9. Khasanov S, Yang B, Su Y, et al (2021) Induced radioactivity at particle accelerators: a short review. Radiation Detection
Technology and Methods. https://doi.org/10.1007/s41605-021-00292-3 10. Patterson HW (2012) Accelerator health physics. Elsevier 11. Schlaff CD, Krauze A, Belard A, et al (2014) Bringing the heavy: carbon ion therapy in the radiobiological and clinical context. Radiation oncology 9:1–19 12. Vaiserman A, Koliada A, Zabuga O, Socol Y (2018) Health impacts of low-dose ionizing radiation: current scientific debates and regulatory issues. Dose-Response 16:1559325818796331 13. Luo Y, Huang S-C, Zhang H, et al (2023) Assessment of the induced radioactivity in the treatment room of the heavy-ion medical machine in Wuwei using PHITS. Nuclear Science and Techniques 34:29. https://doi.org/10.1007/s41365-02301181-8 14. Furuta T, Sato T (2021) Medical application of particle and heavy ion transport code system PHITS. Radiological Physics and Technology 14:215–225 15. Brugger M, Ferrari A, Roesler S, Ulrici L (2006) Validation of the FLUKA Monte Carlo code for predicting induced radioactivity at high-energy accelerators. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 562:814–818 16. Böhlen TT, Cerutti F, Chin MPW, et al (2014) The FLUKA code: developments and challenges for high energy and medical applications. Nuclear data sheets 120:211–214 17. Tujii H, Akagi T, Akahane K, et al (2009) Research on radiation protection in the application of new technologies for proton and heavy ion radiotherapy. Japanese Journal of Medical Physics (Igakubutsuri) 28:172–206
Mulkiiyat (c) 2025 «O‘zMU XABARLARI»
Ushbu ish quyidagi litsenziya asosida ruxsatlangan Kreativ Commons Attribution-NonCommercial-ShareAlike 4.0 International litsenziyasi asosida bu ish ruxsatlangan..
.jpg)
.png)
