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SYNTHESIS, STRUCTURE, AND PROPERTIES OF ACETOACETANILIDE BENZOYLHYDRAZONE

Acetoacetanilide benzoylhydrazone, TGA, Raman, RSA, molecular docking, DprE1, Mycobacterium tuberculosis, 4FDO, hydrophobia, amino acids.

Authors

This study investigates the synthesis, structure, and biological activity of acetoacetanilide benzoylhydrazone. The chemical
structure was confirmed by X-ray diffraction analysis, tautomeric forms were examined using quantum-chemical calculations, and
the crystal structure was analyzed through Hirshfeld surface analysis. Molecular docking results demonstrated effective binding
with the 4FDO protein, indicating that the compound is a promising biologically active agent.