FERULA KUHISTANICA O‘SIMLIGIDAN AJRATILGAN ENDOFIT ZAMBURUG‘LAR IKKILAMCHI METOBOLITLARINING ANTIMIKROBIAL FAOLLIKLARINI O‘RGANISH
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Mazkur maqolada Ferula kuhistanica (kovrak) o‘simligining turli organlari - ildiz, poya va barglaridan besh xil sof holatdagi endofit zamburug‘ ajratib olindi. Tanlab olingan izolyatlar suyuq ozuqa muhitida yetishtirildi va ularning ikkilamchi metabolitlari qutbli erituvchi yordamida ekstraksiya qilindi. Ajratib olingan ikkilamchi metabolitlarning antibakterial va antifungal faolligi turli patogen mikroorganizmlar ishtirokida baholandi hamda yuqori faollikka ega izolyatlar aniqlab olindi. Olingan natijalar shuni ko‘rsatadiki, Ferula kuhistanica o‘simligidan ajratilgan endofit zamburug‘larning ikkilamchi metabolitlari farmatsevtika sohasida antibiotiklarning muqobil manbai sifatida qo‘llanish imkoniyatiga ega.
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