Co(II) NING BENZIMIDAZOL HOSILASI BILAN KOORDINATSION BIRIKMASINING SINTEZI VA TADQIQOTI
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For the first time, a coordination compound of Co(II) ions with 1H-benzimidazole-2-carboxylic acid (1H-BIZ) as a ligand has been synthesized and characterized. The structure of the synthesized complex was investigated using elemental analysis, IR and Raman spectroscopy, as well as differential thermal analysis (DTA). It was established that the composition, structure, and properties of the coordination compounds depend on the nature of the complexing agent and the modes of ligand coordination.
1. Pandurangan A.N., Rana K. Anand, Ahamad P.A., Tiwari A.K. Benzimidazole: A short review of their antimicrobial activities // International Current Pharmaceutical Journal. –2012. –P.110–118. 2. Michele Tonelli, at al. Antiviral activity of 2-phenylbenzimidazole derivatives // Bioorg Med Chem. –2010. -P.2937-2953. doi:10.1016/j.bmc.2010.02.037. 3. Kathleen E. Prosser, Stephanie W. Chang, Felix Saraci, Phuc H. Le, Charles J. Walsb. Anticancer Copper Pyridine Benzimidazole Complexes: ROS Generation, Biomolecule Interactions, and Cytotoxicity // Journal of Inorganic Biochemistry. –2016. -V.167. -P.89-99.
4. 4.Ravichandran Veerasamy, Anitha Roy, Rohini Karunakaran, Harish Rajak. Structure–Activity Relationship Analysis of Benzimidazoles as Emerging Anti-Inflammatory Agents: An Overview // Pharmaceuticals–2021. -V.14. -N7. – P.–663.
5. I. Cheretaev V., Korenyuk I. I. , Nozdrachev A.D. Neurotropic, Psychoactive, and Analgesic Properties of Benzimidazole and Its Derivatives Physiological Mechanisms // Neuroscience and Behavioral Physiology. –2018. –V.48. -N7. –P.381-390. 6. Cheng-Ying Hsieh, et al. Design and Synthesis of Benzimidazole-Chalcone Derivatives as Potential Anticancer Agents // Molecules. –2019. -V. 24. -N18. –P.–3259-3278. doi:10.3390/molecules24183259 7. Guan-Yeow Yeap, et al. Synthesis, molecular structures and phase transition studies on benzothiazole-cored Schiff bases with their Cu(II) and Pd(II) complexes: Crystal structure of (E)-6-methoxy-2-(4-octyloxy-2-hydroxybenzylideneamino) benzothiazole // J. Mol. Struct. – 2012. -V. 1012. – P.1-11.
8. Maria Serratrice, et al. Synthesis, Structural Characterization, Solution Behavior, and in Vitro Antiproliferative Properties of a Series of Gold Complexes with 2-(2′-Pyridyl)benzimidazole as Ligand: Comparisons of Gold(III) versus Gold(I) and Mononuclear versus Binuclear Derivatives // Inorg. Chem. – 2012. –V.51. -N5. P.3161-3171.
9. Slawomir Krawczyk, Maria Gdaniec and Franciszek Saczewski: 1H-Benzimidazole-2-carboxylic acid monohydrate // Acta Crystallographica Section E.–2005. -V. 61, -N12. – P.4185 – 4187. doi:10.1107/S1600536805037505
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