INTERMOLECULAR HYDROARYLATION OF PHENOL WITH SELECTED ACETYLENIC ALCOHOLS
In this work, for the first time, the process of synthesizing 1H-indenols through electrophilic aromatic substitution of phenol by
certain acetylenic alcohols, followed by intramolecular hydroarylation (cyclization) reactions, was studied using the
Yb(OTf) 3 /MeNO 2 catalytic system via the Friedel–Crafts method. A reaction mechanism has been proposed. The influence of
reaction temperature, catalyst, solvent, as well as the amount and nature of the starting materials on the reaction selectivity was
determined. The synthesized compounds were identified, and their characteristic parameters were confirmed using modern
physicochemical methods.
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