ОЦЕНКА ВЛИЯНИЯ ЭКСТРАКТА ЛИСТЬЕВ КАПУСТЫ (BRASSICA L.) НА БИОХИМИЧЕСКИЕ ИЗМЕНЕНИЯ ПРИ МОДЕЛИРУЕМОМ ГЕПАТИТЕ
This experimental study evaluated the hepatoprotective properties of aqueous and alcoholic extracts prepared from cabbage leaves (Brassica L.) in a model of hepatitis induced by carbon tetrachloride (CCl₄). During the study, the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin in blood plasma, and malondialdehyde (MDA) in liver homogenate were measured. The results demonstrated the effectiveness of cabbage leaf extracts in reducing liver damage and enhancing antioxidant protection.
1. Ayaz A., Junaid M., Ullah F. et al. Broccoli: A medicinal food with broad therapeutic potential // Frontiers in Nutrition. – 2020. – Vol. 7. – Article 593.
2. Cho S. J., Yoon S. H., Lee H. J. et al. Protective effects of plant polyphenols against oxidative stress-induced hepatotoxicity // Phytomedicine. – 2015. – Vol. 22(5). – P. 552–561.
3. González R., Ballester I., López-Posadas R. et al. Effects of flavonoids and other polyphenols on inflammation // Phytotherapy Research. – 2016. – Vol. 30(8). – P. 1212–1228.
4. Lim Y., Lee J. E., Kim H. S. et al. Protective effect of broccoli extract against carbon tetrachloride-induced liver injury in rats // Food and Chemical Toxicology. – 2017. – Vol. 109(1). – P. 135–143.
5. Singh A., Bhat T. K., Sharma O. P. Clinical biochemistry of hepatotoxicity // Journal of Clinical Toxicology. – 2011. – Vol. S4. – P. 001.
6. Vidal справочник: Карсил – гепатопротектор на основе силимарина. – 2021. [Электронный ресурс]. Режим доступа: https://www.vidal.ru
7. Wang X., Zhang H., Chen X. et al. Cruciferous vegetable-derived phytochemicals in the prevention of chronic liver diseases // Food and Function. – 2018. – Vol. 9(7). – P. 3375–3390.
8. Zang Y., Igarashi K., Yu C. Antioxidant and anti-inflammatory effects of sulforaphane: Current status and perspectives // Nutrients. – 2020. – Vol. 12(9). – P. 2677.
9. Агапова И. Н., Чернышев А. Л. Применение растительных препаратов при заболеваниях печени // Клиническая фармакология и терапия. – 2018. – Т. 27, № 1. – С. 56–61.
10. Климова И. Д., Громова О. А. Антиоксиданты и печеночная патология: современное представление // Вестник восстановительной медицины. – 2020. – № 2. – С. 43–47.
11. Мясоедов В. Ф., Михалева И. И. Оценка гепатопротекторного действия природных соединений // Экспериментальная и клиническая гастроэнтерология. – 2015. – № 3. – С. 91–96.
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