MENTOL ASOSIDAGI AMINOKISLOTA MURAKKAB EFIRLARINING SINTEZI VA STRUKTURAVIY XOSSALARINI TADQIQ ETISH
In recent years, various derivatives of menthol have been extensively studied in pharmaceuticals, food science, and agrochemistry; however, data on the synthesis of menthol-amino acid esters remain limited. In particular, the relationship between the structural features of menthol–amino acid derivatives and their biological activity has not been sufficiently investigated. Therefore, the novelty of this work lies in the first-time synthesis of menthol esters with glycine, alanine, leucine, and histidine, followed by a comprehensive study of their physicochemical properties and spectral characteristics. The physicochemical properties of the obtained compounds were determined, and their purity was identified using high-performance liquid chromatography (HPLC) with a refractive index detector. The chemical structures were analyzed by infrared (IR) spectroscopy, proton nuclear magnetic resonance (1H NMR) spectroscopy, and mass spectrometry (MS). Based on the obtained results, the functional groups, molecular masses, and general structural features of the synthesized esters were identified and analyzed.
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