Tabiiy fanlar

ANTIMICROBIAL ACTIVITY OF A MIXED LIGANDED Cu2+ COMPLEX OF β-(N-BENZOXAZOLINE-2- THION)PROPIONIC ACID AND 1,10-PHENANTHROLINE

β-(N-benzoxazoline-2-thione) propionic acid, 1,10-phenanthroline, complex, crystal, antimicrobial, bacteria, fungus.

Authors

  • Zoxida MAMADALIYEVA Tayanch doktorant, Namangan davlat universiteti, Namangan, O‘zbekiston, Uzbekistan
  • To‘lqinjon SATTAROV Kimyo fanlari nomzodi, dotsent, University of Business and Science, Namangan, O‘zbekiston, Uzbekistan
  • Odil CHORIYEV PhD, O‘zR FA Bioorganik kimyo instituti, Toshkent, O‘zbekiston, Uzbekistan
  • Jamshid ASHUROV DSc, professor, O‘zR FA Bioorganik kimyo instituti, Toshkent, O‘zbekiston1. Termiz iqtisodiyot va servis universiteti, Termiz, O‘zbekiston2., Uzbekistan

In this article, the antimicrobial activity of the Cu2+ complex with a mixed ligand of β-(N-benzoxazoline-2-thione) propionic acid
(ВОР) and 1,10-phenanthroline was studied in vitro against Escherichia coli, Bacillus subtilis and Candida albicans strains. As a
result of the studies, the maximum bactericidal activity was observed in the [Cu(phen)2(BOP)(H₂O)2]·(BOP)(H₂O)3 sample (0.03
μm/mol) (growth inhibition zone Escherichia coli 35mm ± 0.3mm, Bacillus subtilis 40mm ± 0.4mm and Candida albicans 36mm
± 0.4mm).