β-(N-BENZOKSAZOLIN-2-TION) PROPION-KISLОTA VA 1,10-FENANTROLIN ARALASH LIGANDLI Cu2+ KOMPLEKSINING ANTIMIKROB FAOLLIGI
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Ushbu maqolada β-(N-benzoksazolin-2-tion) propion-kislоta (ВОР), 1,10-fenantrolin aralash ligandli Cu2+ kompleksining patogen
mikroblarga qarshi faolligini in vitro sharoitda Escherichia coli, Bacillus subtilis, Candida albicans shtammlariga nisbatan
o‘rganildi. Tadqiqotlar natijasida [Cu(phen)2(BOP)(H₂O)2]·(BOP)(H₂O)3 namunasida (0,03 mkm/mol) maksimal bakteritsid
faolligi kuzatildi ( o‘sishning ingiberlash zonasi Escherichia coli 35mm ± 0,3mm , Bacillus subtilis 40mm ± 0,4mm va Candida
albicans 36mm ± 0,4mm).
1. Kwanele Ngece, Vuyolwethu Khwaza, Athandwa Paca. The Antimicrobial Efficacy of Copper Complexes: A Review //
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Future Prospects // International Journal of Biomaterials. 2022. doi: 10.1155/2022/6819080
7. Kwanele Ngece, Vuyolwethu Khwaza, Athandwa Paca. The Antimicrobial Efficacy of Copper Complexes: A Review //
National Library of Medicine. 2025. V. 14. № 15. P. 516.
8. Raúl Colorado-Peralta, José Luis Olivares-Romero, Sharon Rosete-Luna. Copper-Coordinated Thiazoles and
Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity // Inorganics.
2023. V. 11. № 5. P. 185
9. Neville S. Ng, Peter Leverett, David E. Hibbs at all. The antimicrobial properties of some copper(II) and platinum(II) 1,10-
phenanthroline complexes // Dalton Transactions. 2013. V. 42. № 9. P. 3196-3209.
10. Graziela V. Rigo, Fernanda G. Cardoso, Michael Devereux at all. Antimicrobial and Antibiofilm Activities of Copper(II)-
1,10-phenanthroline-5,6-pione Against Commensal Bacteria and Fungi Responsible for Vaginal Microbiota Dysbiosis //
2023. V. 80. № 23. P. 383.
11. Shashi Bhushan Chaturvedi, Laxman Gharti Magar, Pretty Chaudhary at all. Bioactive Potential of Guava Leaves against
Bacterial Pathogens // Tribhuvan University Journal of Microbiology. 2025. V.12. № 1. P. 146-150.
12. Z.R.Mamadaliyeva, T.A.Sattarov, J.M.Ashurov. β-(N-benzoksazolin-2-tion) propion-kislоta va 1,10-fenantrolin aralash
ligandli Zn2+ kompleksining antimikrob faolligi. Qo‘qon DPI.Ilmiy xabarlar // 2026. V. 8. № 5. P. 821-826.
Mulkiiyat (c) 2026 «O‘zMU XABARLARI»

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