O‘ZBEKISTON RESPUBLIKASI JIZZAH VILOYATI BAXMAL TUMANINING JANIBUY-SHARQIY QISMIDAN TERILGAN PYRUS PYRASTERNING FLAVONOID TARKIBI
##submission.downloads##
Ushbu ishda O‘zbekiston Respublikasi Jizzah viloyati Baxmal tumanining janubiy-sharqiy qismida o‘suvchi yovvoyi nok (Pyrus pyraster) mevalari ekstraktlarining flavonoid tarkibi natijalari keltirilgan. Yuqori samarali suyuqlik xromatografiyasi (YuSSX) usuli yordamida diod-matritsali deteksiya bilan asosiy flavonoid birikmalar: gall kislotasi, rutin, izokversetin va giperazidlar identifikatsiyalandi va miqdoriy aniqlandi. Flavonoidlarning eng ko‘p miqdori suvli ekstraktlarda aniqlangan bo‘lib, bunda rutin (39,06±0,04 mg/100 g quruq moddaga nisbatan) asosiy birikma sifatida tavsiflandi. Turli erituvchilar (suv, 40% va 70% etanol) ishtirokida ekstragent samaradorligini taqqoslash natijalariga ko‘ra, suv biologik faol moddalarni ajratib olishning optimal sharoiti sifatida baholandi. Tadqiqot natijalari Pyrus pyrasterni farmatsevtika, oziq-ovqat va kosmetika sanoatida qo‘llash uchun tabiiy antioksidantlar manbasi sifatida uning mevalari yuqori potensialga egaligini tasdiqlaydi. Bunda asosiy mezon ekstraktlarni oziqovqat va nutritsevtika funksional mahsulotlarida qo‘llash istiqbollariga qaratilgan.
1. Kumar, S., & Pandey, A. K. (2013). Chemistry and biological activities of flavonoids. Scientific World Journal, 2013, 162750.
2. Li, X., et al. Bioactive compounds in pear cultivars. Journal of Agricultural and Food Chemistry, 2014, Vol. 62(3), pp. 658– 668.
3. Ganeshpurkar, A. Rutin: A therapeutic potential. Chemico-Biological Interactions, 2017, Vol. 273, pp. 154–159.
4. Kolniak-Ostek, J.; Kłopotowska, D.; Rutkowski, K. P. Comparative study of phenolic compounds in wild and cultivated pears. Food Chem. 2020, Vol. 321, 126706.
5. M. Brahem, R. Ouni. IRESA, Университет Суса Франция; INRA, университет Авиньона и Пэ-Дю-Воклюз, Тунис, 2017.
6. J. Kolniak-Ostek, D. Kłopotowska, K.P. Rutkowski. Вроцлавский университет окружающей среды и наук о жизни, Вроцлав, Польша; Научно-исследовательский институт садоводства, Польша, 2020.
7. X. Li, T. Wang, B. Zhou, W. Gao, J. Cao, L. Huang. Тяньцзиньский университет, Тяньцзинь, Китай, 2014. 8. Izabela Rychlińska, Jan Gudej. Qualitative and quantitative chromatographic investigation of flavonoids in Pyrus communis L. flowers. Acta Poloniae Pharmaceutica - Drug Research. 2003 January, Vol. 60(1), pp. 81-5. 9. Yu Geon Lee, Wol Kim, Jeong-Yong Cho, Tae-Il Jeon. Coumaroyl quinic acid derivatives and flavonoids from immature pear (Pyrus pyrifolia nakai) fruit. Food Sci. Biotechnol. 2013, Vol. 22(3), pp. 803-810. 10. Chand, P.; Kumar, H.; Jain, R.; Jain, A.; Jain, V. Flavonoids as omnipotent candidates for cancer management. S. Afr. J. Bot. 2023, Vol. 158, pp. 334–346. 11. Ganeshpurkar, A.; Saluja, A. K. The pharmacological potential of rutin. Saudi Pharm. J. 2017, Vol. 25, pp. 149–164. 12. Chand P., Kumar H., Jain R., Jain A., Jain V. Flavonoids as omnipotent candidates for cancer management. South African Journal of Botany. 2023, Vol. 158, pp. 334–346. 13. Rychlińska, I.; Gudej, J. Qualitative and quantitative chromatographic investigation of flavonoids in Pyrus communis L. flowers. Acta Pol. Pharm. 2003, Vol. 60, pp. 81–85. 14. Lee, Y. G.; Kim, W.; Cho, J.-Y.; Jeon, T.-I. Coumaroyl quinic acid derivatives and flavonoids from immature pear (Pyrus pyrifolia Nakai) fruit. Food Sci. Biotechnol. 2013, Vol. 22, pp. 803–810. 15. Williams, R. J.; Spencer, J. P. E.; Rice-Evans, C. Flavonoids: Antioxidants or signalling molecules? Free Radic. Biol. Med. 2004, Vol. 36, pp. 838–849. 16. Ganeshpurkar, A., & Saluja, A. K. Protective effect of rutin on humoral and cell mediated immunity in rat model. ChemicoBiological Interactions, 2017, Vol. 273, pp. 154–159. 17. Bahare Salehi, Alessandro Venditti, Mehdi Sharifi-Rad, Dorota Kregiel. The Therapeutic Potential of Apigenin. International Journal of Molecular Sciences. 2019, Vol. 20, pp. 1305.
Mulkiiyat (c) 2025 «O‘zMU XABARLARI»
Ushbu ish quyidagi litsenziya asosida ruxsatlangan Kreativ Commons Attribution-NonCommercial-ShareAlike 4.0 International litsenziyasi asosida bu ish ruxsatlangan..
.jpg)
.png)
