2,3-TRIMETILEN-1,2,3,4- TETRAGIDROXINAZOLON-4 BILAN FOSFIT KISLOTANING KABACHNIK-FILDS REAKSIYALARI
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Maqolada 2-aminobenzoy kislotasi va pirrolidon-2 dan turli xil moddalar, masalan, PCl 5 , POCl 3 ishtirokida 2,3-trimetilen-3,4-
digidrobenzo[2,3-d]pirimidin-4-on sintez qilingan. Uning NaBH 4 bilan qaytarilish reaksiyasi amalga oshirilgan. Olingan 2,3-
trimetilen-1,2,3,4-tetragidrobenzo [2,3-d]pirimidin-4-on - karbonil, amin va gidrofosforil birikmasining uch komponentli
birikmasi a-aminofosfonatlarga olib keladi, fosfat kislotasi-formaldegid; uch komponentli sistemadagi aldegidlar;
aminometilfosfon kislota sintezi kondensatsiya reaksiyasiga asoslangan. 2,3- trimetilen-3,4-digidrobenzo[2,3-d]pirimidin-4-on
74% da mahsulot olindi. Reaksiya maxsulotining unumi qayta sintezlarda oshirildi. Tuzilmalar IR va 1H NMR
spektroskopiyalari yordamida tasdiqlangan. NaBH 4 yordamida qaytarilgan va 2,3-trimetilen-1,2,3,4-
tetragidrobenzo[2,3d]pirimidin-4-on sintezidan olingan mahsulot yuqori unum bilan amalga oshirildi. 2,3-trimetilen-1,2,3,4-
tetragidrobenzo[2,3-d]pirimidin-4-on va tegishli aminofosfon kislotalar uch halqali molekula yuqori unum bilan sintez qilindi.
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