ALTERNARIA SP. GB8S NING IKKILAMCHI METABOLIT EKSTRAKTINING VAQT DINAMIKASINI O‘LCHASH
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Ushbu tadqiqotda ekstraktning Staphylococcus aureus, Pseudomonas aeruginosa va Candida albicans shtammlari tomonidan
biofilm hosil bo‘lishini inhibe qilish qobiliyati o'rganildi, bu 62,5 mkg/ml konsentratsiyada 75 dan 78% gacha biofilm inhibisyon
darajasini berdi. Xuddi shu minimal konsentratsiyadan foydalanib, ekstraktning antibioplim faolligi uning inhibitiv ta’sirining
davomiyligi va barqarorligini aniqlash uchun 6-72 soat davomida o‘rganildi. Ushbu tadqiqotlar shuni ko’rsatdiki, Gb8S izolyatidan
ajratilgan ekstrakt qo‘llanilgandan keyin 24 soatgacha o‘z faolligini saqlab qoldi, inhibisyon darajasi 65 dan 71% gacha. 36 soatlik
ta’sirdan so'ng, faollikning asta-sekin 60% dan pastga pasayishi kuzatildi.
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