EPIDEMIOLOGICAL ANALYSIS OF THE PREVALENCE OF TYPE 1 DIABETES MELLITUS IN AN ECOLOGICALLY UNFAVORABLE REGION: THE CASE OF ALMALYK CITY
This study investigated the prevalence characteristics of Type 1 diabetes mellitus in Almalyk city, one of the environmentally
unfavorable and industrially developed regions of the Tashkent Province. Official medical and statistical data for the years 2024–
2025 were analyzed. A comparative assessment of diabetes prevalence rates across different cities and districts of the Tashkent
Province was conducted, and the age-related dynamics of the disease among the population of Almalyk city were determined. The
results showed that by the end of 2025, the number of patients diagnosed with Type 1 diabetes mellitus in Almalyk had increased
by 12.3%. The highest prevalence of the disease was observed in the 50–69-year age group. The findings suggest that environmental
factors, urbanization, and lifestyle characteristics in industrialized areas may contribute to the spread of metabolic diseases among
the population.
1. Hou Z. et al. Exposure to air pollution and the risk of type II diabetes mellitus. Frontiers in Endocrinology. 2024;15:1482063.
2. Arzu O.R., et al. Heavy metals as endocrine disruptors. Journal of Trace Elements and Minerals. 2025.
3. Yousif M.H, Ricardo L-T, Abdul Q, Kinaan F Thaer K.S, Hanieh S.Y, Joelle N.F, Shangwe K, Iman F, Danielle J.G,
Thirumurugan P, Rainer L, M. Hassan M, Sagar B.D. OrganicPollutantsandRiskofType2Diabetes:AsystematicReviewand
Meta-analysis Mayo Clin ProcInnQualut February2026; 10(1):100677 https://doi.org/10.1016/j.mayocpiqo.2025.100677
www.mcpiqojournal.org
4. Parasin N. et al. Outdoor air pollution exposure and the risk of type 2 diabetes mellitus: systematic review and meta-analysis.
Environmental Research. 2025.
5. Zhao C. et al. Metal Mixture Inflammatory Index and diabetes risk in US adults. Scientific Reports. 2025.
6. Vasishta S. et al. Air pollution and its role in the rising burden of type 2 diabetes. Environmental Science and Pollution
Research. 2025.
7. Zheng L. et al. Associations between metal exposure and metabolic syndrome. Frontiers in Public Health. 2025.
8. Alieva A, Alimov A, Khaidarova F, Ismailov S, Rakhimova G. Assessing the Effectiveness of Type 2 Diabetes Screening in
the Republic of Uzbekistan. International Journal of Endocrinology and Metabolism, 20(4), 2022.
9. Qayumov A.J. Sisitema zdravooxraneniya i sovremennoe lechenie diabeta 2 tipa v Uzbekistane. Klinik va profilaktik tibbiyot
jurnali 2024. № 2.
10. Takhirova F, Alikhanova N. Diabetes mellitus in the Tashkent region of Uzbekistan. Jurnal: Endocrine Abstracts, Volume
81, EP1189 (2022) DOI: 10.1530/endoabs.81.EP1189
11. Diabet XII veka. Globalnыe problemi. Lokalnoe reshenie. Posvyaщeniya sovremennыm problemm diabetologii i
tireoidologii konf//Tashkent, 2019.S.378-398.
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