DEVELOPMENT OF ION-SELECTIVE ELECTRODES FOR RAPID DETECTION OF PHARMACEUTICALS BASED ON HETEROPOLYMETALLOPHOSPHATE IONOPHORES
Keywords:
molybdenum- and tungsten-containing heteropoly compounds, ionophores, pharmaceuticals, ion-selective electrodeAbstract
Optimal conditions were selected for the synthesis of sparingly soluble electrode-active materials based on pharmaceutical preparations and heteropoly compounds (HPCs) containing molybdenum and tungsten. The composition and structure of the obtained electrode-active compounds were determined using IR spectroscopy, scanning electron microscopy, X-ray diffraction, and X-ray fluorescence methods. During the conducted studies, ion-selective electrodes (ISEs) based on HPCs were developed for the determination of pharmaceutical substances, and their electroanalytical characteristics were evaluated.
References
1. G.I. Mantrov, I.V. Kobilinsky, S.S. Ryasensky. Ion-selective electrode for the determination of drotaverine in pharmaceutical preparations // Vestnik TeGU. Chemistry Series. 2015, №1, pp. 10–15.
2. S.V. Kharitonov. Transport properties of cation-selective membranes of organic base-containing azo compounds: diffusion and ion flux // Zhurnal Analiticheskoi Khimii. 2003, Vol. 58, №2, pp. 199–206.
3. N.A. El-Ragehy, A.M. El-Kosasy, S.S. Abbas, S.Z. El-Khateeb. Polymeric membrane electrodes for selective determination of central nervous system acting drugs: fluphenazine hydrochloride and nortriptyline hydrochloride // Analytica Chimica Acta. 2000, Vol. 418, №1, pp. 93–100.
4. I. Koryta, K. Shtulik. Ion-Selective Electrodes. Moscow: Mir, 1989. 272 p.
5. M.Yu. Nemilova, N.V. Shvedene. Ion-selective electrodes based on adamantylthiacalix[4]arenes for determination of alkali metal cations // Vestnik Moskovskogo Universiteta. Series 2. Chemistry. 2011, Vol. 52, №1, pp. 48–52.
6. D.-L. Long, Y.-F. Song, C. Ritchie, L. Cronin. Nanoscale polyoxometalate-based inorganic–organic hybrids // Chemical Record. 2011, Vol. 11, №3, pp. 158–171.
7. A.A. Belyustin. Potentiometry: Physicochemical Principles and Applications. St. Petersburg: Lan, 2015. 336 p.
8. Khalil S., Borham N., ll.-Rics M.-A. Piroxicam and tenoxicam selective membrane sen.sors//Anal. Chim. Acta.-2000. Vol.414. P. 215-219.
9. Pinilla-Peñalver, E., Villaseñor, M.J., Contento, A.M., Ríos, Á.Erythrosine B – coated gold nanoparticles as an analytical sensing tool for the proper determination of both compounds based on surface-enhanced Raman spectroscopy // Microchemical Journal. 2020. Vol. 157. Р. 937
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 «JOURNAL OF MODERN CHEMISTRY»

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.



