DETERMINATION OF COPPER (II) IONS USING 5-(O-AMINOPHENYL)-1,3,4-OXADIAZOLE-2-THIONE REAGENT BY ELECTROCHEMICAL METHODS
Keywords:
5-(o-aminophenyl)-1,3,4-oxadiazole-2-thione, chronoamperometry, cyclic voltammetry, electrochemical sensor, complex formation, environmental monitoring.Abstract
The possibilities of highly sensitive and selective electrochemical determination of copper(II) ions using the organic reagent 5-(o-aminophenyl)-1,3,4-oxadiazole-2-thione (HR₁) were studied. Chronoamperometry and cyclic voltammetry were employed to analyze the kinetics and mechanism of the process. The obtained results showed that the reduction of the reagent on the electrode surface was observed at 0.93 V, while the shift of the potential to 0.52 V after the addition of copper(II) ions confirmed the formation of a complex. Based on the cyclic voltammetry and chronoamperometry results, the involvement of two electrons in the reaction calculated. The developed method exhibited a linear relationship in the concentration range of 1.12 to 9.40 μg/mL for copper(II) ions. The results obtained by the "spiked-found" method (R = 0.9948; Sr = 0.013–0.067) confirm the high accuracy, repeatability, and reliability of the method. Due to its low cost, simple preparation, no requirement for expensive laboratory equipment, and rapid analysis, the proposed method is considered as promising for wide application in the ecological and toxicological monitoring of copper(II) ions in soil, food, and biological samples.
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