FENIL-2-XLORPROPIONATNI 4-METOKSIFENOL BILAN NUKLEOFIL ALMASHINISH REAKSIYASI
The article presents for the first time the nucleophilic substitution reactions of phenyl-2-chloropropionte chloride with 4-methoxyphenol under various conditions and the method for the synthesis of phenyl-4-methoxyphenoxypropionate. The nucleophilic substitution reactions were carried out in the presence of benzene, dioxane, DMF, and DMSO solvents, and phenyl-4-methoxyphenoxypropionate was synthesized in DMSO solution with a yield of 90%. The structure of the synthesized new organic substance, phenyl-4-methoxyphenoxypropionate, was confirmed using modern IR, ¹H NMR, and 13C NMR spectra
1. Маматкулов Н.Н. Влияние соотношения реагентов и катализатора на выход реакции хлорацетилирования фенола и изомерных крезолов/ UNIVERSUM: Технический науки. Научный журнал. Москва, 2021. -№4 (82). -С. 77-80.
2. Маматкулов Н.Н. Об одной задаче синтез реакции ацетилирование м-крезола/ Ясауи университетінің хабаршысы. Қозоғистон, 2018. -№2. –С. 43-48.
3. Mamatkulov N.N., Khoshimkhаnova M.A., Devolopment of the mechanism of action and reaction of O-chloracetylation/ International Journal of advanced Research in Science, Engineering and Technology. 2020.-Vol. 7. –Is. 1. -P. 12636-12639.
4. Маматкулов Н.Н. Определение оптимальных условий синтеза п-толилбензоилоксиацетата// Вестник науки и образования научно-методический журнал. Москва, 2020. -№ 10 (88). -часть 2. -С. 19-21.
5. Hariprasada K. Siva, Harikrishnaa G., Zehrab A., Tiwari A.K. Free radical scavenging and α-glucosidase inhibitory activity of (E)-methyl/ethyl-3-(2-hydroxyphenyl)acrylates. Indian Journal of Chemistry, 2021, 60B/1, 111-116.
6. Anusha D., Praveena G., Prakasham R.S., Zehra A., Tiwari A.K. A convenient synthesis and biological activities of N-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides. Indian Journal of Chemistry, 2021, 60B/1, 117-126. DOI:10.56042/ijcb.v60i01.40586.
7. Choriev A., Abdushukurov A.K., Jurayev R., Jurayeva M. Di(2-izopropil-5-metilfenilkarboksimetilen) oksalat sintezi//Kimyo va kim. texn. jurn. Toshkent, 2023, №1, B. 33-35.
8. Mamatkulov N.N., Abdushukurov A.K., Ochilov M. Fenilxloratsetat bilan 2-metilfenolni nukleofil almashinish reaksiyasi orqali fenil-2-metilfenoksiatsetat sintez qilish/NamDU Ilmiy Axborotnomasi. Namangan, 2024. -№11. .-B. 227-231.
9. Mamatkulov N.N., Ochilov M., Pattaeva Z. Synthesis of Organic Fertilizers Based on Phenol and Benzoic Acid Derivatives and Application Technology to Plants/ Journal of Innovative Studies of Engineering Science. Germaniya, 2023. –V. 02. –Is.04. P. 94-97.
10. Mamatkulov N.N., Pattaeva Z. S. Testing the biological activity of some properties of phenylchloracetate in the pass online program/ International Journal of Economy and Innovation. 2023.-V. 37. -Pp. 74-78.
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